SARS-CoV-2 was discovered in January 2020 and since then the virus has spread worldwide, infecting four million people and killing more than 210,000. Unfortunately, so far there is no vaccine or approved treatment for SARS-CoV-2 infection. To date, all drugs available or in development for the treatment of Covid-19 have been shown to be ineffective against SARS-CoV-2. Researchers at the University of California, Berkeley, have recently developed a number of new covid-1-specific antibodies that have been successfully tested on cell cultures, but their ability to kill viruses has not yet been tested on patients. As a result, there is currently no known treatment that is currently approved for use in humans to combat Covid-19.
Researchers at the Molecular Biology Consortium at ALS have discovered an antibody that can neutralize all known SARS-CoV-2 species, including four new onions. As the authors note, this is an important stage because so far, all Covid-19 drugs have been shown to be ineffective against SARS-COV-2. The antibody is now being preclinically tested at the California Institute for Biomedical Research (CIBC) and should be available for further testing and clinical trials in the next few months.
Researchers at the University of California, Berkeley, have recently developed a number of new covid-1-specific antibodies that have been successfully tested on cell cultures, but their ability to kill viruses has not yet been tested on patients. As a result, there is currently no known treatment that is currently approved for use in humans to combat Covid-19.
Researchers at the Molecular Biology Consortium at ALS have discovered an antibody that can neutralize all known SARS-CoV-2 species, including four new onions. As the authors note, this is an important stage because so far, all Covid-19 drugs have been shown to be ineffective against SARS-COV-2. The antibody is now being preclinically tested at the California Institute for Biomedical Research (CIBC) and should be available for further testing and clinical trials in the next few months.
A team of researchers at the University of California, San Francisco has recently launched an antibody-based therapy called "MAB-A3" that involves engineering and testing antibodies on different parts of the virus. As the author writes:
“The goal of this project is to develop a safe and effective antibody for Kovid-1 for as soon as possible. Our approach is to design and test human monoclonal ibibodies in an attempt to find ibentibodies capable of neutralizing SARS-CoV-2.
Researchers at Gilead Sciences have used their advanced drug development process to begin testing several potential treatments on human patients. According to the company, there are five main stages in the process.
2. Drug testing in cell culture
3. Bringing a human patient with covid-1 in front of medicine
4. Investigation of possible side effects
5. Clinical trials
Gilead scientists are now focusing on the "hapten-antibody" they refer to as the "GLS-5700". According to the company, it "protects against both Covid-1 and SARS-Cov-2." However, the process of making it may also allow for “the design, testing and production of immunogenesis”.
They explain that the drug is made up of a "polysaccharide complex" that is "specially formulated to get the immune response from the mucosal immune system."
The company says, “The ability of the GLS-5700 polysaccharide complex to effectively target and induce a rapid mucosal immune response (from the nose and upper airways to the abdomen) is critical to the potential treatment of Covid-19.
The "polysaccharide complex" is not meant to target and attack the virus. This is "to target and activate the mucous immune response". In other words, it is used as a prophylactic to develop "memory" ib antibodies.
In the case of SARS-CoV-2, which is much smaller than the size of the GLS-5700, this can be serious. According to Fauci, Covid-19 has spread to at least 80 countries and has already killed 12,000 people. The virus is expected to continue to spread as long as social distance and home-stay policies remain.
The GLS-5700 is in Phase 1 clinical trials to test its safety. It may soon be available as a preventative measure for those who have been identified as at risk.
"There is no vaccine for SARS-CoV-2 and it is clear that if an effective vaccine for SARS-CoV-2 is available, it is important to start vaccination before infection to reduce viral exposure to the respiratory mucosa." The company said in a press release.
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